61 Comments
User's avatar
RexesRule's avatar

Thanks for a great article. My Doc insisted the jab was safe & effective for me, even though I have a clotting disorder (Protein S deficiency). Despite his scare tactics, I refused to be injected.

Wild Flower 🐝's avatar

Thank you. ⭐️ Great information. An excellent paper to study. It makes sense now.

Julian Gillespie's avatar

thank you Kevin et al,

.. i sought further understanding of these findings from ChatGPT, who/which tried to play it all straight and feed me some mainstream lines somewhat dismissive, at first ..

so I drilled down

then posited the following ..

_______________________

Question:

"Chat, you state "Mainstream pathology does not currently recognize human DNA-rich fibrin clots as a distinct post-vaccination phenomenon, so this remains highly exploratory and outside standard consensus—though worthy of investigation if findings are replicated"; however, Chat, does mainstream pathology regularly encounter and easily recognise host DNA-rich (cfDNA) fibrin clots that are persistent, structurally abnormal, and resist normal breakdown mechanisms?"

Answer:

No, mainstream pathology does not regularly encounter or recognize fibrin clots that are:

-- Rich in host DNA (especially cfDNA or genomic DNA),

-- Structurally abnormal (e.g., rubbery, elastic, or fibrous in a “calamari-like” manner), and

-- Resistant to breakdown by standard fibrinolysis mechanisms (such as plasmin activity).

These features, taken together, are not a routine or well-documented phenomenon in the established pathology literature.

Let’s break this down:

1. cfDNA in Clots – Limited and Contextual Recognition

Cell-free DNA (cfDNA) can appear in the blood and may deposit in clots under some pathological conditions (e.g., cancer, sepsis, autoimmune disease).

In particular, NETosis (a process where neutrophils release DNA to trap pathogens) can lead to DNA-containing clots, but this is:

-- Typically sparse, and

-- Recognized primarily in immunothrombosis, not generalized postmortem clots or systemic clotting disorders.

However, even in NET-associated thrombosis, the volume and mechanical structure of the clot remain within physiologic ranges—not rubbery or undissolvable.

2. “Rubbery” or “Calamari-Like” Clots – Not Recognized

Persistent, elastic, or fibrous clot structures, as described in postmortem reports linked to the COVID-19 mRNA vaccine context, are not recognized in standard pathology handbooks or hematology literature.

Clots typically seen at autopsy are:

-- Postmortem clots: gelatinous, chicken-fat/red currant jelly appearance.

-- Antemortem clots: firm, layered, attached to vessel wall.

A rubbery, resilient clot that resists enzymatic breakdown is not normal, and is not well-characterized or routinely classified in clinical or forensic pathology.

3. Fibrinolysis Resistance – Atypical

-- Fibrin-rich clots are normally broken down via plasmin-mediated fibrinolysis.

-- Resistance to fibrinolysis (as reported in some of these clot analyses) may occur in rare genetic conditions (e.g., α2-antiplasmin excess), but not in the widespread, grossly abnormal manner reported in anecdotal vaccine-linked cases.

Any widespread emergence of such clots post-vaccination would represent a novel pathophysiologic mechanism, not yet defined in hematology textbooks, WHO ICD coding, or peer-reviewed large cohort studies.

Conclusion

So to answer directly:

No, mainstream pathology does not regularly encounter or easily recognize host DNA-rich fibrin clots that are persistent, structurally abnormal, and resist normal breakdown mechanisms. These features, if observed systematically and independently replicated, would warrant classification as a novel clinical and forensic phenomenon.

__________

.. and there, Folks, you have it

touché McKernan et al

merci beacoup

encore

Janiesaysyay's avatar

Julian, ask it to summarize Heparin Induced White Clot Syndrome and all its mechanisms. Then ask for a comparison of how the LNPs and the spike protein from the vaxx could mimic these mechanisms, do a side by side comparison. Then ask it to define the novel phenomenon or ask it if anyone has shown it the phenomenon of Vaccine Induced White Clot Syndrome.

currer's avatar

Thanks for doing this. 👍

MICHAEL O'BRIEN's avatar

Could you please publish a summary version of this report that a retired truck driver can understand? Please...

David Pare's avatar

When things go over my head, I go and read the "conclusion", that provides context, and then I can rescan the post.

MICHAEL O'BRIEN's avatar

The conclusion goes over my head. At my age all I can do is listen to my gut. That's why I am a Pureblood. But I could not make my 20 something daughter understand that it was suspect based on the controlled narrative that shut down debate.

I am very ANGRY!

Unagnu's avatar

It was suspect because it was more or less forced / coerced on people to remain employed to travel etc. When sanctions like that are applied by your own gov't over a relatively harmless for most 'cold' (keeping in mind elderly die all the time of colds) and the 'treatment' is 'experimental gene therapy' not a standard vaccine, you have to wake up and smell the smoke. Something hinky going on.... thank you .gov I'll pass on that... and boy did it take courage and fortitude to not 'go for it'... so so much social pressure and conformity. I found out I am a non conformist par excellence! Raising my glass to other like minded... 20 percent of the population, LOL

Quadriped's avatar

Run the article through Grok and ask for a summary.

MICHAEL O'BRIEN's avatar

I have no idea how to do that.

Beemac's avatar

Claude came up with this:

The authors argue this represents the first genetic study of clots from vaccinated individuals and call for larger studies to identify people who might be at higher genetic risk for vaccine-related clotting events. They suggest genetic screening could help predict who might be more vulnerable to adverse effects.

The study is presented as preliminary evidence that genetic factors may influence susceptibility to vaccine-associated clotting, though the authors acknowledge they cannot prove causation with such a small sample size.​​​​​​​​​​​​​​​​

MICHAEL O'BRIEN's avatar

Thank you for your efforts on my behalf. Sincerely...

Anandamide's avatar

The chatGPT interface I have has been trained for over 500 hours on this topic and doesn't give you narrative advice anymore. But its response to others using it for the first time will not provide the same answer.

here is its summary-

[![Whole Genome Sequencing of Fibrin Clots - by Anandamide](https://tse3.mm.bing.net/th?id=OIF.eugzhsEhoVYAmqZLsaYWew\&pid=Api)](https://anandamide.substack.com/p/whole-genome-sequencing-of-fibrin)

The Substack article titled **"Whole Genome Sequencing of Fibrin Clots"** by Anandamide explores the genetic underpinnings of abnormal fibrin clot formation through comprehensive genomic analysis. The study focuses on identifying high-impact genetic variants that may contribute to excessive or pathological clotting.([anandamide.substack.com][1])

### 🧬 Key Findings

* **Gene Ontology (GO) Analysis**: The researchers examined 2,312 genes associated with thrombosis-related GO terms.([anandamide.substack.com][1])

* **Variant Annotation**: Using the snpEFF tool, they annotated variants to predict their potential impact on protein function.([anandamide.substack.com][1])

* **High-Impact Variants**: The analysis identified several high-impact variants, including frameshift mutations and stop-gained variants, in genes implicated in coagulation and fibrinolysis pathways.

### 🔍 Notable Genes Identified

* **SERPINA2**: A frameshift mutation in this gene, which encodes an alpha-1-antitrypsin-related protein, was highlighted. Although SERPINA2 is less characterized, its relation to protease inhibition suggests a potential role in clot regulation.

* **P2RX5**: A frameshift variant in this purinergic receptor gene may influence platelet aggregation and vascular function.

* **BIN1**: Identified with a frameshift mutation; BIN1 is involved in membrane dynamics and may affect endothelial cell function.

* **SLC6A18**: A stop-gained mutation in this solute carrier gene could impact amino acid transport, indirectly influencing coagulation pathways.

* **PRSS1**: A stop-gained variant in this gene, which encodes trypsinogen, may alter protease activity related to clot breakdown.

### 🧠 Implications

The presence of these high-impact variants suggests a genetic predisposition to abnormal fibrin clot formation. Understanding these mutations provides insight into the molecular mechanisms of thrombosis and may inform personalized therapeutic strategies.

For a more detailed exploration of the study and its findings, you can read the full article here: [Whole Genome Sequencing of Fibrin Clots](https://anandamide.substack.com/p/whole-genome-sequencing-of-fibrin).

[1]: https://anandamide.substack.com/p/whole-genome-sequencing-of-fibrin?utm_source=chatgpt.com "Whole Genome Sequencing of Fibrin Clots - by Anandamide"

currer's avatar

Thanks for doing this.

😊😊 Claude's reply carefully misses the real point about the abnormality of these clots and avoids as much as it elucidates. I suppose it cannot read between the lines or place things in a wider context, but must stick to main points.

Unagnu's avatar

Nano tech materials not addressed at all either... you aren't getting the big picture here, is the combination of elements causing it: genetics (probably already known about), what's in the 'lot' (unknown but SV40, nano particles of graphite or other materials, fake amino acid which does not play well in the body, membrane disruption of the mitochondria your body's power cell(s) so to speak, and on and on. Not just one thing alone.. total disruption of the body systems...oh and we haven't addressed the proteins folding issues either causing prion disease .. uhm.. Alzheimer's incoming...

Markker's avatar

Ask yourself, or anyone, what cures have been found in the last 20 yrs since the Genebank completed? Zilch!

Marc G. Wathelet's avatar

Fantastic work, as usual. Thank you!

Janiesaysyay's avatar

Now THIS is SCIENCE!

Fabulous work Kevin, in your service to humanity!

Thank you! Thank you! YaY! YaY!

Take that Warped Speed hacks!

We are science now!!

Trump Dick Sucker's avatar

Which particular aspects of THIS SCIENCE have you most enthused?

Brandon is not your bro's avatar

Thank you and your dedicated team . The colchicine comment was helpful as well .

Ghostfromthefuture's avatar

I would be interested to learn what the new director of the NIH will say about this post. Surely funding research along these lines will be helpful?

John Goetz's avatar

FYI ... The "Red High Impact snpEFF", "Red Moderate Impact snpEFF", and "Red ALL variants" links are broken.

Anandamide's avatar

Thank you. Don't know how that happened. I replaced the links.

John Goetz's avatar

I’m not knowledgeable in your space, but I agree with your objective to be transparent with your data collection and results. Just making sure no one can claim you are hiding anything 👍🏻

currer's avatar

New report from McCairn.

Amyloidogenic Fibrin Microclotting Following Prenatal mRNA Vaccination Exposure

https://substack.com/home/post/p-164383206

currer's avatar

Am I correct in thinking that the lack of a Pfizer or Moderna sequence in the clots is in fact more worrying? Because it suggests that once initiated, the protein misfolding spontaneously self perpetuates, even in the absence of the original trigger, whether it be virus or vaccine.

Anandamide's avatar

That is the nature of amyloidosis.

They chain react.

The vaccine DNA might show up if we sequenced deeper? But I don’t how long ago it was inhected

currer's avatar

Thank you for your response. There were early suggestions that spike was a necessary component to be present as part of the clots. Does not look like it now. And your work is further evidence that what these clots are is a highly reactive amyloidosis.

Anandamide's avatar

I dont think we have the data to rule that out. Not with this study and I suspect spike is playing a role as its amyloidogenic. We just didnt have the tools to measure spike protein and we didnt sequence RNA. So the mRNA could still be present and we wouldnt have seen it.

currer's avatar

Thanks, I understand now.

"There does NOT appear to be Pfizer or Moderna sequence in the Red or White clots."

This quote only refers to looking for integration into human DNA and could not detect spike mRNA.

Janiesaysyay's avatar

Theoretically the LNPs and the endotoxin from the vaxx could phosphorylate the blood proteins in the same manner that Heparin Sulfate does and produce the White Clots.

I don't know if it can cause the amyloids without the spike protein, which simply cause extra resistance to lysis of the clots.

Either way, I think it was Greg Harrison who said in an interview, the LNPs make the platform unusable because of their tendency to form white clots with blood proteins i.e. "Protein Coronas" I did a couple threads on this "Killer Queen" and "PEG."

currer's avatar

It crossed my mind that the LNP platform is only used in certain countries. Russia China and India did not use LNP tech. The clotting may target the "first world" nations.

mejbcart's avatar

There is a need for some simplicity here...

BILLIONS of humans were injected with one and the same FOREIGN NON-HUMAN Spike gene, embalmers all over the world extract similar looking calamaris out of HUMAN VEINS and ARTERIES

post the injections events, and yet there is NOTHING in this report what would imply SPIKE involvement in the SYNTHETIC GENETIC REPROGRAMMING of the entire human body, because, quote:

"Reads that do map to Pfizer or Moderna are of poor quality with many soft-clipped reads and mismatches. Since there is no spike sequence, we have not searched these reads for integration events."???

How similar to FDA strategy... Do I understand it right here, HUMANS genetics ALONE is 'responsible' for the clots formation, not the Spike gene???

"we performed qPCR of the human house keeping gene RNaseP and followed that up with Whole Genome Sequencing. Both qPCR and Illumina whole genome sequencing confirm this is in fact human DNA. Human DNA is commonly found in clots due to a process known as Neutrophil Extracellular Traps or NETs."

This here is all only about HUMAN genetics, and only 'reaction of genetic predisposition to vaccines', thus it is becoming clear why the authors falsely do not use the proper word of gene therapies for the global injection genocide.

And if it is the Spike which is amyloidogenic why there is no SEARCH FOR A Spike protein pieces/or its genes fragments, in those clots? Because, quote:

"Further, during inquiry into the genetics of thrombotic predispositions, we must remain aware of the fact that the spike protein is amyloidogenic and prior variants associated with thrombotic predisposition may not capture this phenomenon." and doing only a genetic analysis while looking only at 'human genetic predisposition', what about all the reports of SV40 pieces and its definite integration into the human genome?? Now they are suddenly not there in the genome of the clots, apparently representing the human genome???

For the last ~5 YEARS I'm doing AMINO ACID sequence analysis of 'JUST' the INJECTED and expressed SPIKE gene (turning into a synthetic protein) alone, while comparing it to many human proteins, from which there is a LOT of information one can derive and point to lot of the facts about the health issues of the jabs... This GENETICS report says NOTHING at all to me about how the FOREIGN genes are actually affecting the HOST GENES.... Well, the foreign genes conveniently disappeared!

Clearly the HUGE MASS of those clots, can't be 'just human DNA', because if it was, it would imply the human blood after the injections, extracts its own, now 'nasty' DNA out of the body...

signed: PROTEIN CRYSTALLOGRAPHER.

rjt's avatar

The introduction introduces the point that the study is to confirm that the clots being offered are not from other species. As in most studies, the conclusion is that more studies are needed.

I could not find any acknowledgement of grants or support for the work, so we must be grateful for the time and effort expended.

I had been hoping for a protein chemist to produce an antibody which would discriminate infectious spike from injected spike, possibly through the two proline substitution; or maybe even through knowing that the injected version was matched to the Wuhan spike and after 2021 the variants could be recognised. This would be useful for discriminating "Long Covid" from "Long Vaxx" and would allow some determination of cause of death in the "Suddenly and Unexpectedly" cases.

Perhaps consider the spike as a catalyst- you would not necessarily need to see much in the clots.

mejbcart's avatar

sorry forgot to add, I know that this work is IMPORTANT and one should be grateful for any discussion on this clot topic, which DOES NOT exist in main stream 'science'. I'm just extremely ANGRY about the entire global gene therapy crime, which should/could have been prevented by those scientists in power, with CREDENTIALS to 'get audience attention'. It didn't happen, the catalytic event spread like INTENTIONAL chain reaction and now the entire humanity is in serious trouble, with unlimited injuries, countless deaths, including my own family..

mejbcart's avatar

the infectious spike IS the injected Spike. The production of antibodies is not precise enough in my opinion, to distinguish between the 2 versions differing in just those two residues KV-> PP. Protein segments of >10 aa usually contribute to the specificity of any antibody, as some sources state. A simple amino acid sequence test, LIKE THE covid-19 test(!!!), could search for the 'KV' OR the 'PP' larger fragment... This simple test in fact, would actually proof what the 'long covid' and injections covid is, because, if there are only 'PP' versions out there, then we'd know that EVERYTHING actually stems from the genetically modifying injections with the 'PP' version.

I'm talking about this for a LONG TIME, and yet, this OBVIOUS fact does not get any attention.

James's avatar

Maybe you missed the point about a tiny one molecule foreign amaloid seed starting a chain reaction and using the human clotting mechanism.

James's avatar

"Since the vaccines contain human sequences in their UTRs, teasing apart integration events from library construction artifact can be challenging and requires further investigation."

Can you use the 21.6% of the spike not homogeneous to humans?

I bet these guys have the data. https://pubmed.ncbi.nlm.nih.gov/34192262/

Trump Dick Sucker's avatar

Why do you think that paper is relevant? And those authors?

Where do you with get 21.6% ?

Anandamide's avatar

Doesn’t pass a chatGPT screen?

Yes, the body has mechanisms to break down antibody clumps, known as immune complexes, which are crucial for maintaining immune system balance. These clumps can form during immune responses and, if not properly cleared, may contribute to autoimmune conditions.

Mechanisms for Breaking Down Antibody Clumps

1. Phagocytosis by Immune Cells: Macrophages and neutrophils play a pivotal role in clearing immune complexes. They recognize these complexes through Fc receptors and engulf them, leading to their degradation within lysosomes. This process is enhanced by opsonization, where antibodies tag pathogens or complexes for destruction.  

2. Complement System Activation: The complement system, a part of the innate immune response, can be activated by antibody-antigen complexes. This activation leads to the formation of membrane attack complexes that can lyse pathogens and also facilitates the clearance of immune complexes by phagocytes. 

3. Proteolytic Degradation: Enzymes such as proteases can degrade antibody aggregates. This is particularly relevant in therapeutic settings, where engineered antibodies are designed to be more stable and less prone to aggregation. 

4. Cellular Quality Control Mechanisms: Cells have intrinsic systems to manage protein aggregates:

• Chaperone Proteins: Molecular chaperones assist in refolding misfolded proteins and can help disassemble aggregates.

• Ubiquitin-Proteasome System: This system tags misfolded proteins with ubiquitin, marking them for degradation by the proteasome.

• Autophagy: Larger aggregates can be sequestered into autophagosomes and delivered to lysosomes for degradation.   

5. Aggresome Formation: When the proteasome system is overwhelmed, cells can transport aggregates to a centralized location called the aggresome. This sequestration helps in managing the aggregates and facilitates their degradation via autophagy. 

Therapeutic Interventions

In clinical settings, especially concerning therapeutic monoclonal antibodies, preventing and managing aggregation is vital. Strategies include: 

• Protein Engineering: Modifying antibody sequences to reduce aggregation-prone regions. 

• Optimizing Formulation Conditions: Adjusting pH, ionic strength, and adding stabilizing agents to minimize aggregation during storage and administration. 

• Redox Modulating Agents: Incorporating agents like glutathione can help maintain the redox balance, reducing the formation of disulfide-linked aggregates. 

These interventions aim to enhance the stability and efficacy of antibody-based therapies by minimizing unwanted aggregation.

currer's avatar

The McCairn paper found some slight evidence of vaccine components.

https://substack.com/home/post/p-163255744

....qPCR amplification plots demonstrating detection of human reference genes (RNAP), viral spike sequences, and plasmid vector markers (SV40 and Ori) from clot-derived tissue extracts..... Late-cycle amplification signals for SV40 promoter, spike protein coding sequence, and Ori (origin of replication) suggest low-abundance presence of residual plasmid DNA consistent with LNP-based recombinant vaccine components. ..... These results indicate preliminary molecular evidence for incorporation or association of spike vaccine-related material within the clot matrices.

Anandamide's avatar

The sequencing is only at 50X-60X coverage. So it will only see SV40 and Ori that is 4-5 CTs lower than the RNAP internal control. We dont have the depth of sequencing to see what qPCR is reporting

Juli Mination's avatar

Reading Patents instead of worshiping a cult of a self-made and declared detection technologies Build by Eugenicists…

Why Did Harvard’s (now convicted?) Charles M. Lieber Create a U.S. Patent for Using 5G Radiation to Vibrate Corona Virus Particles from Preset Nanotubule Containers?

Systems and Methods for Injectable Devices –PATENT: WO-2015-199784A2

https://patentimages.storage.googleapis.com/ec/8c/f5/5a460ccb123d10/WO2015199784A2.pdf

https://patents.google.com/patent/WO2015199784A2/en

https://julimination.wordpress.com/2024/01/20/who-is-harvards-now-convicted-charles-m-lieber/

https://juli2a5i4.substack.com/p/a-bigger-picture-over-data-health?r=1pk0jl

https://juli2a5i4.substack.com/p/quantum-dots-pseudoscince-and-deadly?r=1pk0jl