An interesting paper bubbled up while I was searching for DNase I inhibitors. This documents a case of BSL2 lab staff triggering false positives for Nucleocapsid C19 RT-qPCR tests. Normally this would go unnoticed and be chalked up to one series of asymptomatic cases of C19 but these folks dug deeper. It appears the same lab was working with plasmids that encode the nucleocapsid gene of SARs-CoV-2 and this plasmid colonized the airways of a few lab staff.
Nothing surprises me any more. Another question that needs to be asked is whether or not the people in this study should also be tested for plasmids as well? After all, what went into the eyes, could well have also gone in the nose:
Curious case of nucleocapsid encoding Plasmids colonizing Lab staff
Nothing surprises me any more. Another question that needs to be asked is whether or not the people in this study should also be tested for plasmids as well? After all, what went into the eyes, could well have also gone in the nose:
https://pubmed.ncbi.nlm.nih.gov/35082653/
Important finding. Thank you.