Personally I never liked any lab isolated CBD or even MJ from your local dealer. When VA allowed growing a few plants in my backyard- WOW, what a difference: no red eyes, dry mouth, paranoia, and extremely spiritual! I focused on high CBD seeds (as heirloom as I can get) and grown them outside organically- no chemicals, full spectrum of the sun, natural stressors like bugs, wind, storms, and of course grown slowly and naturally as possible like Nature intended. And the soil has to be clean because cannabis will soak up those pollutants and heavy metals. Dried and cured over a long time, then cooked and packaged my bottles with a balance of hemp and coconut oils. Good balance of THC/CBD/terpenes/etc... you know- the entourage effect which is all about synergy! Since this was a free gift from nature, I gifted these bottles (and dried herb) out for free to friends, family, neighbors, and pets. Helped them all a lot. I am growing CBG White Buffalo right now, but it's more of a struggle than growing other plants in the past 2 years . The weather has been weird in my area, less bees and insects, and I only saw one butterfly and zero hummingbirds so far.
Matthew Waker once mentioned, IIRC on Joe Rogan, that cannabis (I don't recall what of it) inhibits REM sleep. This seems to be rarely mentioned anywhere. Would seem to be rather important, messing with ability to learn well and all sorts of other things.
The body has three kinds of opiate receptor (delta, kappa and mu) and two kinds of cannabinoid receptor (CB1 and CB2). Anandamide populates both the cannabinoid receptors, and the about 800 milligrams of morphine made daily in our adrenal glands, populates all three opiate receptors. The mu receptors regulate sleep. The CB1 and 2 receptors regulate spasmodic events, including seizures.
Interestingly a common presentation of psychosis includes insomnia, great fatigue (perhaps caused by the insomnia?), and profoundly labile emotions that trigger over anything. It will be interesting to see what is learned from low-level CBD anti-seizure meds, on the lability and restlessness commonly seen during psychotic break.
Other pathways play a role … endorphin and enkephalin pathways , dopamine and seratonin…. Triggered by stress / exercise. Unfortunately pot stores are opening everywhere without really understanding complete mechanisms involved. Buyer beware.
Personally I never liked any lab isolated CBD or even MJ from your local dealer. When VA allowed growing a few plants in my backyard- WOW, what a difference: no red eyes, dry mouth, paranoia, and extremely spiritual! I focused on high CBD seeds (as heirloom as I can get) and grown them outside organically- no chemicals, full spectrum of the sun, natural stressors like bugs, wind, storms, and of course grown slowly and naturally as possible like Nature intended. And the soil has to be clean because cannabis will soak up those pollutants and heavy metals. Dried and cured over a long time, then cooked and packaged my bottles with a balance of hemp and coconut oils. Good balance of THC/CBD/terpenes/etc... you know- the entourage effect which is all about synergy! Since this was a free gift from nature, I gifted these bottles (and dried herb) out for free to friends, family, neighbors, and pets. Helped them all a lot. I am growing CBG White Buffalo right now, but it's more of a struggle than growing other plants in the past 2 years . The weather has been weird in my area, less bees and insects, and I only saw one butterfly and zero hummingbirds so far.
Matthew Waker once mentioned, IIRC on Joe Rogan, that cannabis (I don't recall what of it) inhibits REM sleep. This seems to be rarely mentioned anywhere. Would seem to be rather important, messing with ability to learn well and all sorts of other things.
The body has three kinds of opiate receptor (delta, kappa and mu) and two kinds of cannabinoid receptor (CB1 and CB2). Anandamide populates both the cannabinoid receptors, and the about 800 milligrams of morphine made daily in our adrenal glands, populates all three opiate receptors. The mu receptors regulate sleep. The CB1 and 2 receptors regulate spasmodic events, including seizures.
Interestingly a common presentation of psychosis includes insomnia, great fatigue (perhaps caused by the insomnia?), and profoundly labile emotions that trigger over anything. It will be interesting to see what is learned from low-level CBD anti-seizure meds, on the lability and restlessness commonly seen during psychotic break.
Way over my poor unscientific head. Bottom line. DOES THIS STUFF WORK?
I know how to make CBD oil, and have for a great many years, since I discovered/bumped into Rick Simpson's "Run from the cure", in 1999.
The poor guy had to flee Canada as a result of what he was doing with cannabinoids.
Curing cancer. (For free...)
https://rumble.com/v1pkg5z-run-from-the-cure-the-rick-simpson-story-full.html
"5% of the people think; 10% of the people think they think; and the other 85% would rather die than think." Thomas Edison
"5% of the people think; 10% of the people think they think; and the other 85% would rather die than think." Thomas Edison
Good quote that! No wonder we're so deep in it now!
I'd easily believe the percentages have become 1% / 2% / 97% among the world's population growth since TE's era, certainly after the COVID fiasco.
Other pathways play a role … endorphin and enkephalin pathways , dopamine and seratonin…. Triggered by stress / exercise. Unfortunately pot stores are opening everywhere without really understanding complete mechanisms involved. Buyer beware.