“Never confuse education with intelligence, you can have a PhD and still be an idiot.”
― Richard P. Feynman
We know who the real experts are. They are in their labs with their pipettes and test equipment; they are presenting their findings to parliaments around the world; they are selfless, they are caring; they are exposing a crime against humanity; they are making a huge difference.
Kevin, the difference between you and them is your passion, curiosity. Curiosity equals intelligence. Plus, you’re not protecting your income stream. No conflict of interest.
Well put as always Kevin. One of the posts above does feed into the SV40 virus straw man deflection the fact checkers use (as you have pointed out many times). Because the SV40 virus coincidently did contaminate past vaccines and does cause cancer, it is important we distinguish things and point out their tactical diversions.
In this regard, ID-ing as "regulatory elements from SV40" is more useful than referring to "SV40 virus DNA" (which can imply the viral genome containing the oncogenic T-antigen). The SV40 T-antigen (whose gene is not in the Pfizer DNA template) directly causes cancer due to its inhibition of tumor suppressor. But the SV40 virus is especially problematic because it does contain DNA regulatory elements that both enable nuclear entrance of host cells and, if integrated into the genome, amplify the expression of nearby genes. In fact, this SV40 promoter/enhancer element works so well that it has been adapted for use in laboratory transfection of mammalian cells (experiments to induce cultured cells to express specific proteins by adding the encoding DNA to the cell culture medium). To increase the chance that your gene of interest gets into the nucleus and incorporated into the cell's genome (in the case of stable/permanent transfection), the SV40 promoter/enhancer element is included in the DNA plasmid containing the gene for the target protein. This plasmid is then mixed with cationic lipid to enable the DNA to penetrate the cell membranes (akin to the mRNA LNP formulation).
Pfizer's rationale for using a plasmid intended for cell transfection to serve as a template for mRNA production is puzzling to say the least. Typically, one would use simpler plasmids optimized for run-off transcription to generate RNA. You would still have the DNA contamination problem, but at least not pieces carrying the DNA nuclear targeting sequence (DTS; this is the 1st half of the SV40 promoter/enhancer sequence). All the speculation on the odds of each step happening or not, is nonsense. The key aspects have not been measured. For example, these DNA fragments could still be associated in a complex with other DNA pieces in the LNP remnants, and thereby help pull other crap through the nuclear pore. If I had to guess who might have some insights on this, I would look to those working at places that develop the commercial plasmids for stable transfection. They probably measure genomic integration with minimal SV40 sequence elements.
Finally, hearing less of the arbitrary “safe levels" is a good sign. DNA outside a cell is like throwing spaghetti noodles through a wall. The NLP puts the spaghetti into a missile.
It's impossible to keep up with this crap... but this is about as close as I've ever seen. Saving as a potential future debunk bunk debunker.
Hey, I grew up with a rotary phone and write my own apps now. Otherwise a good smackdown, but don't tempt our citation-counting overlords...